The first results have been announced from what is seen as South Africa's most closely fought elections since the African National Congress (ANC) came to power 30 years ago.
With results from around 19% voting districts counted so far, the ANC is leading with 43%, followed by the DA with 25%.
The radical EFF has about 9%, while the uMkhonto weSizwe Party (MK Party) of former President Jacob Zuma is on around 8%.
Final results are expected over the weekend.
The initial results suggest the ANC will lose its parliamentary majority for the first time since Nelson Mandela led the party to victory following the end of the racist system of apartheid in 1994.
South Africa's News24 website has projected that the party's final vote could be around 42%, down from the 57% it obtained in the 2019 election.
The initial results show that the ANC is suffering heavy losses to MK, especially in KwaZulu-Natal, bringing down its national vote.
KwaZulu-Natal is the home region of Mr Zuma, and the province with the second-highest number of votes.
Mr Zuma caused a major shock when he announced in December that he was ditching the ANC to campaign for MK.
Although he has been barred from running for parliament because of a conviction for contempt of court, his name still appeared on the ballot paper as MK leader.
Wednesday's election saw long lines of voters outside polling stations late into the night across the country.
The key issues for voters were widespread corruption in government, high levels of unemployment and rampant crime.
One electoral official in Johannesburg told the OceanNewsUK the queues were reminiscent of the historic 1994 election, when black people could vote for the first time.
Sifiso Buthelezi, who voted in Johannesburg's Joubert Park - the biggest polling station in South Africa - told the OceanNewsUK: "Freedom is great but we need to tackle corruption."
Change has been a recurring sentiment, especially among young voters.
Ayanda Hlekwane, one of South Africa's "born-free" generation, meaning he was born after 1994, said despite having three degrees he still doesn't have a job.
“I’m working on my PhD proposal so that I go back to study in case I don’t get a job,” he tells the OceanNewsUK in Durban.
But Mr Hlekwane said he was optimistic that things would change.
A record 70 parties and 11 independents were running, with South Africans voting for a new parliament and nine provincial legislatures.
Analysts say this shows that many people are disillusioned with the ANC.
"We are entering the next phase of our democracy, and it is going to be a big transition," political analyst Richard Calland told the OceanNewsUK.
"We will either become a more competitive and mature democracy, or our politics will become more fractured."
The main opposition party, the Democratic Alliance (DA), has signed a pact with 10 other parties, agreeing to form a coalition government if they get enough votes to dislodge the ANC from power.
But this is highly unlikely, with the ANC expected to remain the biggest party, putting it in pole position to lead a coalition if its support does drop below 50%.
South Africans do not directly vote for a president. Instead they vote for members of parliament who will then go on to elect the president.
So current President Cyril Ramaphosa is likely to remain in power.
More than 27 million people were registered to cast their ballots, including a high percentage of young voters, who could prove decisive.
Artist Njabulo Hlophe, 28, said young people in South Africa tend to get marginalised but, "this is as much our country as our parents... they're leaving it to us, so someone that really cares about the young people is someone I’m really looking at".
Support for the ANC is expected to be higher among the older generation.
One 89-year-old woman, Elayne Dykman, told the OceanNewsUK in Durban she hoped that young people in South Africa did not take their vote for granted.
